US Patent Issued to THE BROAD INSTITUTE, Massachusetts Institute of Technology on Feb. 24 for "CRISPR enzymes and systems" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,774, issued on Feb. 24, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).

"CRISPR enzymes and systems" was invented by Feng Zhang (Cambridge, Mass.), David Arthur Scott (Cambridge, Mass.), Winston Xia Yan (Cambridge, Mass.), Sourav Choudhury (Cambridge, Mass.) and Mattias Heidenreich (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments disclosed herein are directed to engineered CRISPR-Cas effector proteins that comprise at least one modification compared to an unmodified CRISPR-Cas effector protein that enhances binding of the CRISPR complex to the bindi...