US Patent Issued to The Brigham and Women's Hospital on Oct. 6 for "Gene therapy for neurodegenerative disorders using polynucleotide silencing and replacement" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,411, issued on Oct. 6, was assigned to The Brigham and Women's Hospital Inc. (Boston).

"Gene therapy for neurodegenerative disorders using polynucleotide silencing and replacement" was invented by Kimberley S. Gannon (Boston), Neil R. Hackett (Boston) and Martin Goulet (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to nucleic acid expression cassettes and vectors for the treatment of neurodegenerative disorders. Methods of treating neurodegenerative disorders such as Alzheimer's disease, frontotemporal dementia, frontotemporal lobar degeneration, Pick's disease, Lewy body dementia, memory loss, cognitive impairment, and...