ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,327, issued on Feb. 24, was assigned to The Brigham and Women's Hospital Inc. (Boston).

"Methods and compositions for treating sleep apnea" was invented by Luigi Taranto Montemurro (Brookline, Mass.) and D. Andrew Wellman (Wayland, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions for the treatment of conditions associated with pharyngeal airway muscle collapse while the subject is in a non-fully conscious state, e.g., sleep apnea and snoring, comprising administration of (i) a norepinephrine reuptake inhibitor (NRI) and (ii) a non myorelaxing hypnotic and/or 5-HT2A inverse agonist or antagonist."

The patent was filed on...