US Patent Issued to The Brigham and Women's Hospital, The General Hospital on Feb. 3 for "Gene therapy for Alzheimer's disease" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,334, issued on Feb. 3, was assigned to The Brigham and Women's Hospital Inc. (Boston) and The General Hospital Corp. (Boston).

"Gene therapy for Alzheimer's disease" was invented by Jie Shen (Brookline, Mass.) and Raymond J. Kelleher III (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides, among other things, human codon-optimized sequences encoding presenilin 1, and methods for using the sequences in gene therapy to treat neurodegenerative diseases including, but not limited to Alzheimer's disease, frontotemporal dementia, frontotemporal lobar degeneration, Pick's disease, Lewy body dementia, memory loss,...