ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,608, issued on Dec. 16, was assigned to The Brigham and Women's Hospital Inc. (Boston) and The General Hospital Corp. (Boston).

"Gene therapy for Alzheimer's disease" was invented by Jie Shen (Brookline, Mass.) and Raymond J. Kelleher III (Brookline, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides, among other things, methods for using presenilin based gene therapy to treat neurodegenerative dementia including, but not limited to Alzheimers disease, frontotemporal dementia, frontotemporal lobar degeneration, Picks disease, Lewy body dementia, memory loss, and cognitive impairment including mild cognitive impairme...