US Patent Issued to The Brigham and Women's Hospital, Massachusetts Institute of Technology, University of Massachusetts on April 14 for "Reprogramming cells into homeostatic microglia" (Massachusetts Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,942, issued on April 14, was assigned to The Brigham and Women's Hospital Inc. (Boston), Massachusetts Institute of Technology (Cambridge, Mass.) and University of Massachusetts (Westborough, Mass.).

"Reprogramming cells into homeostatic microglia" was invented by Oleg Butovsky (Boston), Vladimir Litvak (Holden, Mass.), William Ralvenius (Somerville, Mass.) and Li-Huei Tsai (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for obtaining populations of reprogrammed M0-homeostatic tolerogenic microglial cells. The methods include providing an initial population of monocytes, e.g., peripheral blood monocytes ...