ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,245, issued on Sept. 8, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Compositions and methods for inhibiting T cell exhaustion" was invented by Crystal L. Mackall (Redwood City, Calif.), Rachel Lynn (Redwood City, Calif.), Evan Weber (Redwood City, Calif.) and Elena Sotillo (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to T cell compositions and methods of using the same in the context of therapy and treatment. In particular, the invention provides T cells that are modified (e.g., genetically and/or functionally) to maintain functionality unde...