US Patent Issued to The Board of Trustees of the Leland Stanford Junior University on Oct. 20 for "Human cellular model for investigating cortico-striatal-midbrain neural pathways" (California Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,767,927, issued on Oct. 20, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Human cellular model for investigating cortico-striatal-midbrain neural pathways" was invented by Sergiu P. Pasca (Menlo Park, Calif.) and Yuki Miura (Menlo Park, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Human striatal and midbrain organoids or spheroids are generated in vitro, which may be generated at least in part from human pluripotent stem (hPS) cells. Such spheroids model the regions of the human brain and comprise specific sets of cells that are associated with the striatum, including mature medium spiny neu...