ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,195, issued on Nov. 3, was assigned to The Board of Trustees of the Leland Stanford Junior University.
"Orthogonal safety switches to eliminate genetically engineered cells" was invented by Matthew H. Porteus (Stanford, Calif.), Michael K. Cromer (Stanford, Calif.), Renata Martin (Stanford, Calif.), Jonas Fowler (Stanford, Calif.) and Kyle Loh (Stanford, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for depletion of pluripotent cells. In one embodiment of the invention, methods are provided for depletion of pluripotent cells from a mixed population of differentiated cells and stem cells, to provide a popu...