ALEXANDRIA, Va., May 26 -- United States Patent no. 12,636,317, issued on May 26, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Manipulation and use of antigen-specific regulatory T cells" was invented by Naresha Saligrama (Redwood City, Calif.), Mark M. Davis (Atherton, Calif.) and Jing Li (Redwood City, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for isolating, manipulating and using for therapeutic and other purposes, mammalian, MHC Class I restricted, antigen-specific regulatory T cells. The regulatory T cells can be characterized as CD8+ cells that specifically suppress the responses of self-reactive an...