ALEXANDRIA, Va., March 24 -- United States Patent no. 12,584,149, issued on March 24, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Nuclease-mediated genome editing of primary cells and related kits" was invented by Daniel P. Dever (Stanford, Calif.), Rasmus O. Bak (Stanford, Calif.), Ayal Hendel (Stanford, Calif.), Waracharee Srifa (Stanford, Calif.) and Matthew H. Porteus (Stanford, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain aspects, the present invention provides methods for inducing a stable gene modification of a target nucleic acid via homologous recombination in a primary cell, such as a primary blood cell and/or a primary mes...