ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,161, issued on July 28, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Mechanical and biochemical activation and control of skeletal stem cells for cartilage regeneration" was invented by Michael T. Longaker (Atherton, Calif.), Charles K.F Chan (Redwood City, Calif.) and Matthew Philip Murphy (Palo Alto, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Methods and compositions are provided for the regeneration of articular cartilage by activating skeletal stem cells with a combination of (i) mechanical and (ii) biochemical stimulus. The mechanical stimulus can be an acute local injury. The bi...