ALEXANDRIA, Va., July 28 -- United States Patent no. 12,691,160, issued on July 28, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Engineered fibroblast growth factor 1 variants with increased proteolytic stability" was invented by Sung Jin Park (Stanford, Calif.) and Jennifer R. Cochran (Stanford, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods of screening for proteolytically stable growth factor variants, including, for example variants of human fibroblast growth factor 1 (FGF1) The present invention also provides for FGF1 variants comprising at least one amino acid substitution, an amino acid deletion, an am...