ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,077, issued on July 14, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Generating populations of human blood and blood vessel progenitors from pluripotent stem cells" was invented by Kyle M. Loh (Piscataway, N.J.), Lay Teng Ang (Stanford, Calif.), Alana T. Nguyen (Stanford, Calif.), Jonas Fowler (Stanford, Calif.) and Irving L. Weissman (Stanford, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Methods are provided for the efficient differentiation of hPSCs into HSC-like cells and endothelial cells in defined, monolayer conditions solely using extracellular signals to guide differentiation. ...