ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,638, issued on Dec. 16, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).
"Methods of producing epimerases and benzylisoquinoline alkaloids" was invented by Christina D. Smolke (Stanford, Calif.), Stephanie Galanie (Stanford, Calif.), Isis Trenchard (Stanford, Calif.), Catherine Thodey (Stanford, Calif.) and Yanran Li (Stanford, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting th...