ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,815, issued on April 21, was assigned to The Board Institute Inc. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).
"Self-diversifying systems and methods of use thereof" was invented by Feng Zhang (Cambridge, Mass.) and Jonathan Leo Schmid-Burgk (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "A diversity-generating system comprising: a polynucleotide comprising: a variable region within a sequence encoding a protein or polypeptide, wherein the system is configured to generate a library of diversified molecules with an efficiency of 80% as measured by number of the diversified molecules in total numbe...