US Patent Issued to Texas Tech University System on March 17 for "Mutant DNase1L3 with improved serum half-life" (Texas Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,571, issued on March 17, was assigned to Texas Tech University System (Lubbock, Texas).

"Mutant DNase1L3 with improved serum half-life" was invented by Peter Keyel (Lubbock, Texas), Roger B. Sutton (Lubbock, Texas) and Jon McCord (Lubbock, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes a mutant Dnase1LS having at least about a 95% identity with a nucleic acid sequence encoding the protein of SEQ ID NO: 2-8 for a mutant Dnase1LS comprising at least one mutation for post-translational modification or attachment of a molecule to the mutant Dnase1LS to increase the serum half-life of the mutant Dnase1LS, nucleic aci...