ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,841, issued on May 19, was assigned to Tenaya Therapeutics Inc. (South San Francisco, Calif.).
"Adeno-associated virus with engineered capsid" was invented by Christopher A. Reid (South San Francisco, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides recombinant adeno-associated virus (rAAV) virions with an engineered capsid protein identified using a high-throughput sequencing screen or rational design. In particular, the disclosure provides AAV5 virions and capsid proteins with increased transduction efficiency in cardiac cells, increased cell-type selectivity, and/or other desirable properties."
The patent was ...