US Patent Issued to Tenaya Therapeutics on March 3 for "Optimized expression cassettes for gene therapy" (California Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,647, issued on March 3, was assigned to Tenaya Therapeutics Inc. (South San Francisco, Calif.).

"Optimized expression cassettes for gene therapy" was invented by Huanyu Zhou (South San Francisco, Calif.) and Christopher A. Reid (South San Francisco, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In some aspects, cardiac-specific expression cassettes are provided herein. In some aspects, provided herein is an expression cassette comprising a polynucleotide sequence encoding a gene product for therapy of a heart disease, wherein the polynucleotide sequence is operably linked to promoter (e.g., a cardiac-specific promoter), and optionally an enh...