ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,950, issued on June 2, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).
"Autoinjector comprising high concentration formulation of vedolizumab" was invented by Nobel T. Truong (Milford, Mass.) and Willow Diluzio (Westford, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Anti-alpha4beta7 integrin antibody liquid formulations are described that have a high concentration of antibody, e.g., 90 mg/ml or more, have a viscosity suitable for injection for subcutaneous delivery, including by self-administration by the patient. In certain embodiments, formulations can be used in combination with an autoinjector having a suitable force of del...