US Patent Issued to Takeda Pharmaceutical on Feb. 17 for "Nucleic acid-containing lipid nano-particle and use thereof" (Japanese Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,551,561, issued on Feb. 17, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).

"Nucleic acid-containing lipid nano-particle and use thereof" was invented by Shinobu Kuwae (Kanagawa, Japan) and Satoru Matsumoto (Kanagawa, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a lipid nanoparticle containing the following (a) to (c): (a) a nucleic acid encoding a chimeric antigen receptor (CAR) or an exogenous T cell receptor (TCR); (b) a cationic lipid; and (c) a non-cationic lipid. The present invention also provides a CAR- or exogenous TCR-expressing immunocyte obtained by introducing the lipid nanoparticle into...