US Patent Issued to Takeda Pharmaceutical on Feb. 17 for "Compositions and methods for inhibiting cytochrome P450 family 7 subfamily a member 1 (CYP7A1) expression" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,050, issued on Feb. 17, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).

"Compositions and methods for inhibiting cytochrome P450 family 7 subfamily a member 1 (CYP7A1) expression" was invented by Bernard Allan (Wellesley, Mass.), Brian Ko (San Diego), Pawan Kumar (San Diego), Naim Nazef (San Diego) and Jason Pickens (Chula Vista, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "RNAi agents (e.g., CYP7A1 RNAi agents) for inhibiting the expression of the CYP7A1 gene, compositions including the RNAi agents conjugated to a targeting moiety, and methods of use are described. Also disclosed are pharmaceutical compositions including one...