US Patent Issued to Tagworks Pharmaceuticals on Sept. 15 for "Chemically cleavable group" (Dutch Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,444, issued on Sept. 15, was assigned to Tagworks Pharmaceuticals B.V. (Nijmegen, Netherlands).

"Chemically cleavable group" was invented by Marc Stefan Robillard (Eindhoven, Netherlands), Ronny Mathieu Versteegen (Eindhoven, Netherlands), Wolter Ten Hoeve (Eindhoven, Netherlands) and Raffaella Rossin (Eindhoven, Netherlands).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactic...