ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,361, issued on May 12, was assigned to Syngenta Crop Protection AG (Basel, Switzerland).
"Fusion proteins for DNA base editing" was invented by Jianping Xu (Beijing) and Jiang Li (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods and compositions for modifying a target site in the genome of a cell. Fusion proteins including one or more DNA binding domains and one or more heterologous domains, such as DNA modifying domains, connected by improved linker sequences are provided. Codon optimized polynucleotides encoding fusion proteins including one or more DNA binding domains and one or more heterologous doma...