US Patent Issued to SUZHOU BRIGHTHOPE PHARMATECH on Jan. 20 for "Process for the production of levetiracetam and intermediates thereof" (Chinese, American Inventors)

ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,528,770, issued on Jan. 20, was assigned to SUZHOU BRIGHTHOPE PHARMATECH Co. LTD. (Jiangsu Province, China).

"Process for the production of levetiracetam and intermediates thereof" was invented by Songzhou Hu (Princeton, N.J.), Lijun Deng (Hubei, China), Wen Yu (Hubei, China) and Zhen Song (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is disclosed an improved process for the racemization of (R)-Alpha-ethyl-2-oxo-1-pyrrolidineacetic acid in a solution of alkali hydroxide. The process comprises heating a crystalline suspension of the racemic (RS)-Alpha-ethyl-2-oxo-1-pyrrolidineacetic acid at a temperature from 100deg C. to 250deg C. to in...