US Patent Issued to Sun Yat-sen University on March 17 for "System for inducing mutation based on optimized activation-induced cytidine deaminase" (Chinese Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,553, issued on March 17, was assigned to Sun Yat-sen University (Guangzhou, China).

"System for inducing mutation based on optimized activation-induced cytidine deaminase" was invented by Xionglei He (Guangzhou, China), Li Liu (Guangzhou, China), Chang Ye (Guangzhou, China), Kehui Liu (Guangzhou, China) and Shanjun Deng (Guangzhou, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides a mutant protein of activation-induced cytidine deaminase, wherein the mutant protein has the following mutations when compared to hsAID: T82I, K10E, K34E, E156G, 181*, S38C, H130R, V152A, R174G, and T110A. The present application also ...