ALEXANDRIA, Va., May 19 -- United States Patent no. 12,629,396, issued on May 19, was assigned to SUN YAT-SEN UNIVERSITY CANCER CENTER (Guangdong, China).
"Application of bacteria in preparation of synergist for immune checkpoint inhibitor" was invented by Ruihua Xu (Guangdong, China) and Xia Zhao (Guangdong, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention discloses an application of bacteria in preparation of a synergist for an immune checkpoint inhibitor. The bacteria are active bacteria or inactive whole-cell gut microbiota. By using a monobacterial oral preparation of human endogenous gut microbiota Alistipes combined with an immune checkpoint inhibitor, an anti-tumor immune protective...