ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,494, issued on June 23, was assigned to Sumitomo Pharma Co. Ltd. (Osaka, Japan).
"Optically active bridged piperidine derivative" was invented by Seiji Kamioka (Toyonaka, Japan), Naoaki Shimada (Takatsuki, Japan), Hitoshi Ban (Nishinomiya, Japan), Kazuto Yamazaki (Ikoma, Japan), Akihiko Arakawa (Odawara, Japan) and Wataru Hirose (Suita, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the compound of formula (1a) wherein a-d and p are 1 or 2, R1-R4 are hydrogen atom or the like, and R18 is -CF3 or the like, or a pharmaceutically acceptable salt thereof, which has an anticancer effect by inhibiting the binding bet...