US Patent Issued to Sumitomo Chemical on May 12 for "Plasmid addiction system to drive desired gene expression" (Massachusetts, Washington Inventors)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,363, issued on May 12, was assigned to Sumitomo Chemical Co. Ltd. (Tokyo).

"Plasmid addiction system to drive desired gene expression" was invented by Matthew de la Pena Mattozzi (Boston), Daniel Kim (Carlisle, Mass.) and Sonya Clarkson (Renton, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a Plasmid Addiction System for the stabilization of expression plasmids encoding proteins of interest. The invention uses a succinate cycle optimization to ensure the expression of plasmid(s) of interest. By ensuring that plasmids of interest contain genes necessary in the succinate cycle, the system ensures that the passage...