US Patent Issued to ST. JUDE CHILDREN'S RESEARCH HOSPITAL on Sept. 22 for "Chimeric antigen receptors with CD20 safety switch" (Tennessee Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,001, issued on Sept. 22, was assigned to ST. JUDE CHILDREN'S RESEARCH HOSPITAL INC. (Memphis, Tenn.).

"Chimeric antigen receptors with CD20 safety switch" was invented by Mireya Paulina Velasquez (Memphis, Tenn.), Stephen Gottschalk (Germantown, Tenn.), Janice Riberdy (Memphis, Tenn.), Albert Zhou (Memphis, Tenn.), Byoung Ryu (Memphis, Tenn.), Abishek Vaidya (Memphis, Tenn.) and Giedre Krenciute (Memphis, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides chimeric antigen receptors (CARs), particularly CARs that have enhanced antitumor properties and/or can be regulated by safety switches. Also provided are polypep...