ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,102, issued on July 14, was assigned to St. Jude Children's Research Hospital Inc. (Memphis, Tenn.).
"miRNAS for reducing ventricle enlargement" was invented by Stanislav S. Zakharenko (Collierville, Tenn.) and Tae-Yeon Eom (Memphis, Tenn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention is directed to methods and compositions for treating a disease associated with ventricular enlargement such as 22q11 deletion syndrome (22q11 DS) and schizophrenia (SCZ) by replenishment of decreased levels of miR-382-3p and/or miR-674-3p or inhibition of dopamine receptor Drd1 in ependymal cells."
The patent was filed on July 23, 2020, under Applicatio...