ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,766,132, issued on Oct. 20, was assigned to SOFTKEMO PHARMA CORP. (Canada).
"Lyophilized bendamustine-cyclodextrin composition" was invented by Kishore Patel (Pierrefonds, Canada) and William Dickheiser (Glen Mills, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are lyophilized compositions comprising bendamustine and sulfobutylether beta-cyclodextrin (SBECD) which (a) comprise a molar excess of SBECD relative to bendamustine; (b) do not contain mannitol; and (c) possess a water content of less than about 1% by weight. Such compositions may be prepared in the form of a well-formed cake and exhibit desirable storage stability. The ly...