ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,125, issued on June 16, was assigned to SIRONAX LTD. (Grand Cayman, Cayman Islands).
"Azetidine cyclic ureas" was invented by Zhaolan Zhang (Beijing), Zhiyuan Zhang (San Diego), Yaning Su (Beijing) and Yanping Xu (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are azetidine cyclic urea compounds that inhibit cellular necrosis and/or human receptor interacting protein 1 kinase (RIP1), including corresponding sulfonamides, and pharmaceutically acceptable salts, hydrates and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof with a...