ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,838, issued on June 2, was assigned to SINGAPORE HEALTH SERVICES PTE LTD (Singapore).
"Method of modulating sensitivity to tyrosine kinase inhibitor" was invented by Fui Teen Chong (Singapore), Dorival Mendes Rodrigues-Junior (Singapore), Narayanan Gopalakrishna Iyer (Singapore), Hui Sun Leong (Singapore), Daniel Shao-Weng Tan (Singapore) and Darren Shen Yon Toh (Singapore).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to methods of increasing sensitivity of an epidermal growth factor receptor (EGFR)-related cancer to EGFR tyrosine kinase inhibitor (TKI) comprising administering a therapeutically effective amount of EGFR isoform...