ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,435, issued on April 7, was assigned to SIMPHOTEK INC. (Newark, N.J.).

"Interstitial photodynamic therapy" was invented by Karl Beeson (Princeton, N.J.), Evgueni Parilov (Brooklyn, N.Y.) and Mary Potasek (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of administering interstitial photodynamic therapy to a target region of a patient may include receiving information associated with the target region, an initial photosensitizer concentration, a plurality of initial photosensitizer photokinetic rate parameters, and a threshold treatment dose for a photosensitizer, the threshold treatment dose being a threshold photodynamic the...