ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,484, issued on June 23, was assigned to Shenzhen TargetRx Inc. (Shenzhen, China).
"Substituted piperidines as bruton's tyrosine kinase inhibitors" was invented by Yihan Wang (Shenzhen, China) and Qingfeng Xing (Shenzhen, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A fused bicyclic compound having an effect in inhibition of the activity of a tyrosine kinase, and preparation and use thereof are disclosed. In particular, a compound of formula (IV) or a pharmaceutically acceptable salt, a stereoisomer, a solvate, a hydrate, a polymorph, a prodrug or an isotopic variation thereof, as well as a pharmaceutical composition including the same are di...