ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,610, issued on Aug. 18, was assigned to SHANGHAI ZHIMENG BIOPHARMA INC. (Shanghai).
"Preparation method for hepatitis B virus nucleocapsid inhibitor" was invented by Gang Liu (Shanghai), Bo Liang (Shanghai), Huanming Chen (Shanghai) and Zhaojian Jiang (Pudong New Area Shanghai, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A method for preparing a hepatitis B virus nucleocapsid inhibitor is provided. Specifically, the method involves a novel procedure for preparing a compound represented by formula (I) (each group is as defined in the description) by an optimization process. The method can significantly enhance the yield, improve the product ...