ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,229, issued on Dec. 2, was assigned to SHANGHAI MEDICILON INC. (Shanghai).
"Indole derivative and application thereof" was invented by Feng Ren (Shanghai), Yubin Lv (Shanghai), Hailong Wang (Shanghai), Yueying Ren (Shanghai), Chunlin Chen (Shanghai), Yangchun Luo (Shanghai), Jinna Cai (Shanghai) and Bangliang Li (Shanghai).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to an indole derivative shown in general formula (I-1) and its use in preparing drugs for preventing and/or treating indications of S1P receptor related disorders. The indole derivative of the invention is replaced by R1, R2, R5, and R6 at different sites respectiv...