ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,596, issued on April 14, was assigned to Shanghai Hui Tian Jin Ze Biotech Co. Ltd. (Shanghai).

"Anti-tumor pharmaceutical composition based on immune checkpoint blockade and use thereof" was invented by Biao Zhang (Shanghai) and Sanhong Liu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is an anti-tumor pharmaceutical composition based on immune checkpoint blockade and use thereof. The anti-tumor pharmaceutical composition comprises: paroxetine hydrochloride, and a T-cell enhancer, wherein the T-cell enhancer is at least one of vitamin E and thymosin. Through a series of in vitro and in vivo experiments, cannabidiol and p...