US Patent Issued to Seikagaku on Sept. 29 for "Method for producing an exdotoxin measuring agent" (Japanese Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,748,115, issued on Sept. 29, was assigned to Seikagaku Corp. (Tokyo).

"Method for producing an exdotoxin measuring agent" was invented by Hikaru Mizumura (Tokyo), Maki Aizawa (Tokyo) and Toshio Oda (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method for rapidly and highly sensitively measuring endotoxin relies on an endotoxin-measuring agent, which includes a factor C derived from Tachypleus tridentatus that does not have His-tag sequence at the C-terminus, a factor B of a horseshoe crab, and a proclotting enzyme of a horseshoe crab. Each of these proteins can be a recombinant protein obtainable by being expressed using a stably expressing c...