ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,862, issued on April 21, was assigned to SEEGENE INC. (Seoul, South Korea).

"Detection of target nucleic acid sequences by PTO cleavage and extension assay" was invented by Jong Yoon Chun (Seoul, South Korea) and Young Jo Lee (Seoul, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to the detection of a target nucleic acid sequence by a PTOCE (PTO Cleavage and Extension) assay. The present invention detects a target nucleic acid sequence in which the PTO (Probing and Tagging Oligonucleotide) hybridized with the target nucleic acid sequence is cleaved to release a fragment and the fragment is hybridized with t...