US Patent Issued to Secarna Pharmaceuticals on July 14 for "Modified antisense oligonucleotide for inhibition of FoxP3 expression" (German Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,680,098, issued on July 14, was assigned to Secarna Pharmaceuticals GmbH & Co. KG (Marburg, Germany).

"Modified antisense oligonucleotide for inhibition of FoxP3 expression" was invented by Frank Jaschinski (Puchheim, Germany), Richard Klar (Munich), Sven Michel (Bernried, Germany) and Julia Festag (Eggenfelden, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention refers to an oligonucleotide comprising 12 to 25 nucleotides, wherein at least one of the nucleotides comprises a modification selected from the group consisting of a bridged nucleic acid such as LNA, ENA, a 2'Fluoro modified nucleotide, a 2 O-Methyl modified nucleotide...