US Patent Issued to Scribe Therapeutics on Feb. 17 for "Engineered class 2, type V repressor systems" (California Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,037, issued on Feb. 17, was assigned to Scribe Therapeutics Inc. (Alameda, Calif.).

"Engineered class 2, type V repressor systems" was invented by Jason Fernandes (Redwood City, Calif.), Ross White (Concord, Calif.), Sean Higgins (Alameda, Calif.), Sarah Denny (San Francisco), Benjamin Oakes (El Cerrito, Calif.) and Emeric Jean Marius Charles (Berkeley, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to gene repressor systems comprising catalytically-dead Class 2 CRISPR proteins and one or more transcription repressor domains linked to the catalytically-dead Class 2 CRISPR protein as a fusion protein, as well as a guide ...