ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,505,542, issued on Dec. 23, was assigned to SCREEN Holdings Co. Ltd. (Kyoto, Japan).
"Threshold determination method" was invented by Saya Shibata (Kyoto, Japan) and Hiroshi Ogi (Kyoto, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "A threshold determination method includes a region specification step of specifying cell regions corresponding to individual cells in an image obtained by imaging the biological specimen, a determination step of setting temporarily a threshold for staining density quantitatively indicating the degree of staining of the cell region, comparing the staining density and the threshold for each of the cell regions and determ...