US Patent Issued to Sarepta Therapeutics, Massachusetts Institute of Technology on March 31 for "Processes for preparing phosphorodiamidate morpholino oligomers via fast-flow synthesis" (Massachusetts Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,306, issued on March 31, was assigned to Sarepta Therapeutics Inc. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).

"Processes for preparing phosphorodiamidate morpholino oligomers via fast-flow synthesis" was invented by Kyle A. Totaro (Cambridge, Mass.), Mark D. Simon (Cambridge, Mass.), Ming Zhou (Cambridge, Mass.), Hong Zong (Cambridge, Mass.), Gunnar J. Hanson (Cambridge, Mass.) and Bradley L. Pentelute (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are processes for preparing an oligomer (e.g., a morpholino oligomer). The synthetic processes described herein may be advantageous...