US Patent Issued to Sapience Therapeutics on Feb. 17 for "Modified BCL9 mimetic peptides" (New York, Pennsylvania Inventors)

ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,552,846, issued on Feb. 17, was assigned to Sapience Therapeutics Inc. (Tarrytown, N.Y.).

"Modified BCL9 mimetic peptides" was invented by Barry Jay Kappel (Pelham, N.Y.), Gene Merutka (Phoenixville, Pa.), Jimmy Andrew Rotolo (Port Washington, N.Y.) and Erin E. Gallagher (Bronx, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are BCL9 mimetic peptides having a modified a-helical homology domain-2 (HD2) region and, optionally, a cell-penetrating region, compositions comprising the BCL9 mimetic peptides, and methods of inhibiting proliferation of and/or promoting cytotoxicity in a neoplastic cell using the BCL9 mimetic peptides."

The patent ...