ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,709, issued on Sept. 15, was assigned to Sanegene Bio USA Inc. (Woburn, Mass.).

"Small interfering RNA targeting CFB and uses thereof" was invented by Xin Geng (Oklahoma City), Chunyang Zhang (Burlington, Mass.), Shiyu Wang (Belmont, Mass.) and Weimin Wang (Winchester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure relates to isolated oligonucleotides comprising duplex regions targeting human CFB mRNA, and delivery systems, and compositions comprising the same, and methods of using the same for inhibiting or downregulating CFB gene expression."

The patent was filed on March 19, 2026, under Application No. 19/572,773.

*For fu...