ALEXANDRIA, Va., May 26 -- United States Patent no. 12,636,290, issued on May 26, was assigned to Saint Louis University (St. Louis).
"BET inhibitors for modulating DUX4 expression in FSHD" was invented by Marvin J. Meyers (Wentzville, Mo.), Francis M. Sverdrup (Lake Saint Louis, Mo.), Timothy Caldwell (Lawrence, Kan.) and Jonathan Oliva (Manchester, Mo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides BET inhibitors of the formula: wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods of treating a patient comprising administering a bromo- and extra-terminal (BET) domain inhibitor for the treatment...