US Patent Issued to Rznomics on Sept. 15 for "Trans-splicing ribozyme specific to ApoE4 RNA and use thereof" (South Korean Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,701, issued on Sept. 15, was assigned to Rznomics Inc. (Yongin-si, South Korea).

"Trans-splicing ribozyme specific to ApoE4 RNA and use thereof" was invented by Seong-Wook Lee (Seoul, South Korea) and Seung Ryul Han (Yongin-si, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a trans-splicing ribozyme specific to Alzheimer's disease, and a use thereof. The trans-splicing ribozyme replaces RNA of genes that cause or increase the risk of Alzheimer's disease with RNA of genes that are beneficial for the treatment of the disease, thereby reducing the expression of the disease-causing genes and increasing the e...