US Patent Issued to Rutgers, The State University of New Jersey on May 12 for "CD147 chimeric antigen receptors and methods of use" (New Jersey Inventor)

ALEXANDRIA, Va., May 12 -- United States Patent no. 12,624,102, issued on May 12, was assigned to Rutgers, The State University of New Jersey (New Brunswick, N.J.).

"CD147 chimeric antigen receptors and methods of use" was invented by Dongfang Liu (Millburn, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Modified single chain variable fragments (scFv) that specifically bind CD147 are provided. Also provided are chimeric antigen receptors (CARs) including the modified CD147 scFv, nucleic acids encoding the CARs, vectors including the nucleic acids encoding the CARs, and immune cells expressing the CARs. Methods of treating a subject with cancer including administering to the subject an immune cell expres...